
Florida licenses nurse practitioners as APRNs through the Florida Board of Nursing; a new graduate needs an RN license from any US jurisdiction, a master's or higher NP degree, national certification sent by the certifying body, proof of malpractice coverage or exemption, Livescan fingerprints and a $110 fee. Practice runs under a written protocol with a supervising physician until the APRN registers for autonomous practice, which requires 3,000 supervised clinical hours in the previous five years, graduate coursework in differential diagnosis and pharmacology, a clean five-year record and primary care practice.
Florida issues a single APRN license that covers nurse practitioners, nurse midwives, nurse anesthetists, clinical nurse specialists and psychiatric nurses. For a new FNP or AGNP graduate the path has two phases: first the license itself, which the Florida Board of Nursing reviews within a statutory 30-day window once the file is complete, and then the practice arrangement, which for almost every new graduate means a written protocol with a supervising physician. Florida added a third phase in 2020: after 3,000 supervised hours an APRN in primary care may register for autonomous practice and drop the protocol.
The Florida Board of Nursing, operating within the Department of Health's Division of Medical Quality Assurance (MQA), licenses APRNs under Chapter 464 of the Florida Statutes and Chapter 64B9 of the Florida Administrative Code. The Board of Medicine has a smaller role: a supervising physician must notify it within 30 days of entering or ending a protocol with an APRN under section 458.348. Applications, renewals and the autonomous registration all run through the MQA Services Portal.
The Board's APRN licensing page sets out the standard pathway:
For applicants already licensed as an APRN in another state, the MOBILE endorsement route needs two years of active practice in the previous four, no discipline in five years, verification from each licensing state, NCSBN score transfer and the same $110 fee; the Board states that initial review of new applications can take up to 10 business days and that the license is issued within 7 days once requirements are met.
The Board does not list certifying bodies on the application page; it relies on the statutory requirement for national specialty certification and asks the certifier to send proof. For family and adult-gerontology primary care, the two national certifiers are NPCB and ANCC, and either credential supports the certified nurse practitioner designation. The certification must be kept current for every renewal, so a lapse in national certification also puts the Florida license at risk.
Florida's default arrangement meets the American Association of Nurse Practitioners' definition of restricted practice: section 464.012(3) requires an APRN to practice "within the framework of an established protocol that must be maintained on site," and a physician licensed under chapter 458, 459 or 466 supervises and directs the course of medical treatment. The physician files notice of the protocol with the Board of Medicine within 30 days of starting and within 30 days of ending it. A primary care physician may not supervise more than four offices in addition to the primary practice location without being on site, which matters when a group hires one physician to cover several clinics. The rule that once listed the required contents of a protocol (64B9-4.010) was repealed in 2017, so the protocol's form is agreed between you, the physician and the employer, subject to the statute.
Section 464.0123 lets the Board register an APRN for autonomous practice when the applicant:
Autonomous practice is limited to primary care, which the statute names as family medicine, general pediatrics and general internal medicine, plus nurse midwifery. Autonomous APRNs may admit, manage and discharge facility patients and sign documents normally requiring a physician's signature, may not perform surgery beyond subcutaneous procedures, and must give new patients written information about their qualifications and the nature of autonomous practice. The Board's FAQ states there is no fee to apply for the registration; the application is reviewed for completeness within 30 days and stays valid for one year. Certified registered nurse anesthetists are not eligible.
Florida does not issue a separate prescribing number. Under the protocol (or the autonomous registration) an APRN may prescribe, dispense, administer or order any drug. Controlled substances carry extra conditions from section 464.012:
Federal DEA registration is applied for separately after the state license is issued, using the Florida practice address.
APRN licenses renew every two years in three groups, expiring at midnight Eastern time on April 30 or July 31 of the renewal year (the Board's page currently lists April 30, 2027, April 30, 2028 and July 31, 2028 for the three groups). The fee is $60 when renewed before expiration, $115 after expiration plus delinquency fees, and $175 once a 120-day delinquency notice has issued. Dispensing practitioners pay an additional $100. APRNs are not required to renew the Florida RN license.
| CE requirement (Board renewal page) | Hours |
|---|---|
| General hours from a state or national nursing CE accreditor | 16 |
| Prevention of medical errors | 2 |
| Florida laws and rules | 2 |
| Human trafficking (every renewal) | 2 |
| Safe and effective prescription of controlled substances (every renewal) | 3 |
| Recognition of impairment in the workplace (every other renewal) | 2 |
| Domestic violence (every third biennium, in addition to the total) | 2 |
| HIV/AIDS (one time, before the first renewal) | 1 |
The Board's page gives the total as 24 hours per biennium with domestic violence on top. A nurse certified by an NCCA- or ABSNC-accredited specialty program is exempt from the general CE requirement, but not from the 3-hour controlled substances course or the 2-hour human trafficking course. If the license was issued for less than a full biennium, 1 hour of CE per month held applies. Autonomous APRNs complete 10 additional graduate-level continuing education credits per cycle and submit an updated financial responsibility form at renewal. All CE is reported through CE Broker, not mailed to the Board.
| Stage | What to expect |
|---|---|
| File assembly (certifier letter, malpractice proof, Livescan) | Start before graduation; the certifier letter is usually the slowest item |
| Board review | Statutory review within 30 days of a complete application |
| Protocol and Board of Medicine notice | Signed on hire; physician files notice within 30 days |
| DEA registration | After the license issues |
| Autonomous registration | After 3,000 supervised hours; reviewed within 30 days; no fee |
| Item | Florida |
|---|---|
| Regulator | Florida Board of Nursing (Department of Health, MQA) |
| Application and licensure fee | $110 |
| RN license required | Any US jurisdiction; Florida RN renewal optional afterward |
| Default practice authority | Restricted: protocol with a supervising physician kept on site |
| Autonomous registration | 3,000 supervised hours in 5 years, 3 + 3 graduate semester hours, 5 clean years, $100,000/$300,000 coverage, primary care only, no fee |
| Schedule II | 7-day supply limit (psychiatric exception) |
| Renewal | Every 2 years; $60 before expiration |
| CE | 24 hours including 3 on controlled substances; autonomous APRNs add 10 graduate-level credits |
Every figure above came from the Florida Board of Nursing site and the Florida Statutes as of November 2026; confirm the current fee, renewal date and rule text with the Board before you submit an application.
Common follow-up questions on Registration & Licensure.
No. Section 464.0123 requires at least 3,000 clinical practice hours under physician supervision within the five years before the application, so the earliest realistic point is about 18 months of full-time practice after licensure, and only in primary care (family medicine, general pediatrics, general internal medicine) or midwifery.
Florida requires national specialty certification for initial licensure and every renewal of a certified nurse practitioner license, and the Board asks the certifying body to send proof directly. Both NPCB and ANCC are the recognized certifiers for family and adult-gerontology primary care NPs; confirm your credential with the Board before you apply.
Yes, under the protocol and with DEA registration, but the statutory formulary limits a Schedule II prescription to a 7-day supply, except psychiatric medications prescribed by a psychiatric nurse, and controlled substances for psychiatric conditions in patients under 18 may be prescribed only by psychiatric nurses.
The Board's renewal page states that APRNs are not required to renew their Florida RN license; it is optional. The APRN license renews on its own biennial cycle for $60 when renewed before expiration.
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